Which serum level is most likely to be increased in a patient with liver disease?

Increased serum levels of Alanine Aminotransferase (ALT) are commonly observed in patients with liver disease. ALT is an enzyme primarily found in the liver, and when liver cells are damaged or inflamed, as seen in various liver disorders, ALT is released into the bloodstream, leading to elevated serum levels. This makes it a key biomarker for assessing liver health and function.

In contrast, while Creatinine can indicate kidney function, it is not specifically correlated with liver disease. Hemoglobin levels can be affected by various conditions, but they do not directly indicate liver function or damage. Albumin, a protein produced by the liver, is typically decreased in liver disease due to impaired synthesis, rather than increased. This demonstrates the specific role of ALT as a marker for liver pathology, firmly establishing its relevance in the context of liver disease diagnosis.